Today we will talk about a drug that can be found in almost every home medicine cabinet. People resort to it at the slightest ailment without any consultation with a doctor - it has a reputation as an almost harmless medicine. In addition to its well-known formula, widely advertised in domestic and foreign media, it is also found in so-called fat burners (where it is represented by extract from white willow bark - White Willow). So what is aspirin? How and for what indications should it be used?
Aspirin or acetylsalicylic acid was invented in 1869. It is a derivative of salicylic acid (see formulas), which has been used as an antipyretic and anti-inflammatory agent. Its sodium salt, called “salicylic soda,” remained in the arsenal of doctors for a long time and is still used in some cases. However, pure salicylic acid is an extremely caustic substance and has a harmful effect on the mucous membranes of the gastrointestinal tract. Acetylsalicylic acid is less caustic mainly due to the “closed” phenolic hydroxy group.
ECA (ephedrine, caffeine, aspirin)[edit | edit code]
ECA
is a combination of three drugs: ephedrine, caffeine and aspirin, which is used in bodybuilding and fitness to lose weight and gain relief. The term ECA is an acronym that includes the initial letters of its constituent drugs. ECA-based sports nutrition became especially popular in the 1990s, when there were hundreds of different types of fat reduction supplements on the market, but later the ECA combination was banned in many countries around the world (USA, Canada, Russia). This is due to the abuse and use of ephedrine as a precursor for the production of narcotic substances.
Efficacy of ECA (ephedrine, caffeine, aspirin)[edit | edit code]
Placebo-controlled studies have led to a clear conclusion: ECA (standard dosage) is effective for burning fat. The combination of ephedrine, caffeine, and aspirin demonstrated statistically significant superiority over placebo, with no serious side effects.[1]
A meta-analysis of data showed that ECA increased fat loss by 1-3 kg per month, without additional interventions (exercise, diet).[2] The effectiveness of the ECA combination increases dramatically when performing aerobic training and following a low-calorie diet.
Interestingly, the combination of caffeine and ephedrine is much more powerful compared to taking each component separately. A special study was conducted that lasted six months. Obese patients followed a diet and received either caffeine (200 mg/day dosage), ephedrine (20 mg/day dosage), a combination of caffeine and ephedrine (200 mg + 20 mg/day dosage), or placebo. The most effective formula was caffeine plus ephedrine. Those taking it lost 16.8 kg versus 13.2 kg for those taking placebo.
Side effects
Side effects from the drug occur due to overdose or prolonged use by athletes. Since Aspirin is an acid, its effect on the gastric mucosa will be irritating.
The negative effect of the drug can manifest itself in the form of the following pathological conditions:
- gastritis with subsequent development of gastric ulcer;
- tinnitus and hearing loss due to the toxic effect of Aspirin on the auditory nerve;
- allergic reaction due to individual intolerance to Aspirin;
- anemia;
- increased sweating.
Side effects among bodybuilding athletes are rare, since Aspirin and drugs containing it are prescribed by a sports medicine doctor. Monitoring the concentration of the drug in the blood of athletes is carried out using laboratory methods.
Side effects and harm to health[edit | edit code]
Data on serious side effects of ECA are based only on isolated cases of self-referral, while patients usually had a predisposition or pathology of the cardiovascular system that existed before starting to use ECA. [6]
In studies of ECA on healthy people, no serious complications were recorded during or after use of the drugs. Thus, the combination of ephedrine, caffeine and aspirin can be considered relatively safe. Exaggeration of the dangers of ECA is due to ignorance of factual data and anti-drug propaganda, nothing more.
Secrets of losing weight using a pharmacy
Everyone knows that excessive blood thickness is dangerous; and most choose aspirin as the main cure for this problem. This drug has a wide spectrum of action, so it is prescribed very often. Due to the fact that the side effects on the body from taking aspirin are mild, therapy can last for a very long time. It is for this reason that older people often take this drug regularly for many years. Aspirin appeared in the 19th century in Germany and was initially used as an analgesic for rheumatism, but very soon other beneficial effects of the drug were discovered, which is why it gained enormous popularity.
All materials on the tutknow website.
ECA course (ephedrine, caffeine, aspirin)[edit | edit code]
The optimal ratio of ephedrine, caffeine and aspirin is 1:10:10 or 1:10:15. Converted to the dosage of active ingredients (one portion of ECA): ephedrine - 25 mg, caffeine - 250 mg, aspirin - 250 mg. Up to three such servings are usually taken per day. It is not recommended to take ECA in the evening due to the development of insomnia.
The duration of the ECA course is 1-2 weeks, after which you need to take a break for 1 week, then the ECA course can be repeated. Longer courses should not be taken, as the effect quickly decreases and addiction develops.
Features of taking ephedrine are described in the main article: Ephedrine
To increase the effectiveness of the ECA course, you need to:
- Do aerobic exercise
- Follow a diet to lose weight
- Take sports nutrition for weight loss
Bronholitin, caffeine and aspirin, how to take for weight loss
Aspirin was invented and put into mass production years ago by the doctor Felix Hoffmann and still surprises with its properties. At the same time, aspirin is used not only in medicine, which everyone knows, but is also widely used in everyday life, not for its intended purpose, as they say. More on this below. And in more detail, low-acid soil infected with a fungus can be “Cure” with aspirin. It is enough to dissolve the tablet per liter of water and water the “Problem” bed with it. Due to the reaction of aspirin with the electrolyte, the battery will briefly charge, which may be enough to start the car.
Fat burners in the pharmacy are available to every person who wants to lose excess weight. These substances have different principles of action, but a similar result - a slim and toned figure.
Notes[edit | edit code]
- “In total, these suggest that herbal ephedra/caffeine herbal supplements, when used as directed by healthy overweight men and women in combination with healthy diet and exercise habits, may be beneficial for weight reduction without significantly increased risk of adverse events.” CN Boozer1, PA Daly, P Home, JL Solomon, D Blanchard, JA Nasser, R Strauss and T Meredith “Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial” Int J Obes May 2002, Volume 26 , Number 5, Pages 593-604
- Paul G. Shekelle, MD, PhD; Mary L. Hardy, MD; Sally C. Morton, PhD; Margaret Maglione, MPP; Walter A. Mojica, MD, MPH; Marika J. Suttorp, MS; Shannon L. Rhodes, MFA; Lara Jungvig, B.A.; James Gagné, MD "Efficacy and Safety of Ephedra and Ephedrine for Weight Loss and Athletic Performance: A Meta-analysis" JAMA. 2003;289:1537-1545
- Rawson ES, Clarkson PA. ephedrine as an ergogenic aid. Performance-enhancing Substances in Sport and Exercise. Ed Bahrke MS, Yesalis CE. Human Kinetics. 2002.
- Horton TJ, Geissler CA. Post-prandial Thermogenesis with ephedrine, Caffeine and Aspirin in Lean, Predisposed Obese and Non-obese women. Int J Obes Relat Metab Disorder 1996 Feb;20(2):91-95.
- Horton TJ, Geissler CA. Aspirin Potentiates the Effect of ephedrine on the Thermogenic Response to a Meal in Obese but not Lean Women. Int J Obes 1991 May;15(5):359-366.
- “Prescribed ephedrine/caffeine was not associated with a substantially increased risk of adverse cardiovascular outcomes in this study.” Jesper Hallas, Lars Bjerrum, Henrik Støvring and Morten Andersen “Use of a Prescribed Ephedrine/Caffeine Combination and the Risk of Serious Cardiovascular Events: A Registry-based Case-Crossover Study" American Journal of Epidemiology 2008 168(8):966-973
How to take aspirin to thin your blood correctly
VIDEO ON THE TOPIC: Face mask with aspirin.
The best RECIPES of face masks with aspirin https://youtu.be/iIYlFIeeS_Y
Aspirin for heels is an unconventional but effective way to use a medicine with a long-standing proven track record. Traditional medicine and cosmetology have long used the practice of unusual treatment using the simplest medications. Iodine, hydrogen peroxide, activated carbon and aspirin have long become common means of treatment at home and in beauty salons. Aspirin, or acetylsalicylic acid, is one of the most famous non-steroidal anti-inflammatory drugs.
Claims that cinnamon is beneficial for weight loss are based on scientific research on the beneficial properties of cinnamon.
Operating principle of ECA:
The main active element of ECA is ephedrine. It is used to stimulate the central nervous system, similar in effects to methamphetamines.
Ephedrine leads to stimulation of the production of protein structures (there is an increase in muscle volume) and to a decrease in the percentage of fat and its consumption in the form of bioenergy. The susceptibility of cellular receptors in muscles and adipose tissue under the influence of stimulating ephedrine increases, the processes of tissue growth (muscle mass) and fat loss occur more easily and quickly. Ephedrine inhibits the synthesis of its agonists, replacing them with itself, and because of this phenomenon, dependence on ephedrine occurs.
Ephedrine also tends to increase body temperature, under such circumstances the number of calories burned increases noticeably. Ephedrine does a good job of increasing blood sugar levels, making it possible to endure long, high-intensity physical activity.
Weight loss in the human body occurs due to the effects of stress hormones (catecholamines: adrenaline and norepinephrine). Through beta receptors, both hormones act on fat, oxidizing it into glycerol and acids.
Ephedrine has the property of influencing the sympathetic region of the central nervous system, its main function is the release of norepinephrine - this is what acts on the body and increases the rate of weight loss.
In medical practice, ephedrine is also used to eliminate bronchospasms.
Taking ephedrine leads to slower intestinal motility and dilation of the eye pupils (mydriasis)
The next active element, caffeine, increases the tone of the body, “accelerates” the central nervous system, increases heart rate and slightly increases the temperature of the skin. Caffeine improves mental performance, increases resistance to fatigue and sleep.
At low dosages, caffeine stimulates the nervous system ; at high doses, it inhibits the functions of the central nervous system.
Caffeine and ephedrine in combination - the effectiveness of use is multiplied several times.
Aspirin for weight loss: how to take, reviews. Women's magazine Delafe.ru
Women are ready to do almost anything for a thin waist and slender legs. Today, there are many dubious ways to lose weight: using activated carbon, baking soda, etc. One of the most popular methods today is losing weight with aspirin. Does this product work and is it effective?
Aspirin for weight loss: to be or not to be?
Despite the fact that doctors strongly recommend losing weight through proper nutrition and exercise, many are looking for easier ways. On the forums you can read positive reviews about weight loss using a medication such as Aspirin. Is it worth using this product?
First of all, we would like to remind you that the drug is not intended for weight loss. It has completely different indications for use and properties, so of course, doctors do not recommend using it for weight loss.
Aspirin contains acetylsalicylic acid as its main component. This substance lowers body temperature, reduces inflammation and relieves pain. As for weight loss, it will not give you the desired result if you eat poorly and lead a passive lifestyle.
Is it possible to lose weight on aspirin? The answer is negative, since the effectiveness of the product has not been proven in practice. Many have already tried the drug for weight loss and most are disappointed. Not surprising, because aspirin does not have fat-burning properties. Yes, it really can speed up cellular metabolism, but it does not burn subcutaneous fat and does not remove extra pounds. Therefore, you should not have any illusions; moreover, taking the drug in such dosages disrupts metabolic processes.
How to take aspirin for weight loss?
If you decide to try this drug for weight loss, you need to stick to a certain dosage and not increase it. Otherwise, side effects may occur in the form of nausea, headache and weakness.
You need to take aspirin on a full stomach, after meals, one or two tablets are enough. Never take the drug on an empty stomach, as this will cause heartburn and abdominal pain. Take the tablet with a glass of water or juice or milk.
What is the maximum dose? You can take no more than 300-325 mg of aspirin per day, stick to this dosage. You can divide it into 2-3 doses if desired.
Contraindications for use
Not everyone can use this product. It should not be taken by people who suffer from stomach and intestinal diseases. The drug is also contraindicated for pregnant and breastfeeding women, people with problems with the kidneys, heart and blood vessels.
If your general condition worsens after taking aspirin, stop using it in the future. Perhaps this is how your body reacts to any components that are in its composition.
Check out our post Weight Loss Soda
To date, no studies have been able to confirm the effectiveness of aspirin for weight loss. Not surprising, because the product has nothing to do with weight loss and is intended for completely different purposes.
Aspirin for weight loss: reviews
- Anna: “I also entertained myself with illusions and relied on aspirin; I haven’t been able to lose the desired 10 kg for a long time. I took it for about two weeks and didn’t notice any changes in weight at all. I realized that this was another useless scam...”
- Irina: “For about a month I tried to eat right, walked a lot in the fresh air and drank aspirin. I lost about 3 kilograms. But I don’t know what the reason is - either dietary restrictions or aspirin.”
- Inna: “I only lasted a week, three days later terrible heartburn appeared, which then had to be treated with medications. I’m not going to repeat this experiment again.”
Whether or not to use aspirin for weight loss is your decision. But if you value your health, give up this idea and use healthy techniques to lose weight.
Women's online magazine Delafe.ru
delafe.ru
Disadvantages of such weight loss
Ephedrine, aspirin and caffeine for weight loss stimulate certain nerve centers. This starts the process of increasing body temperature, and it is this factor that affects the acceleration of metabolism.
But do not forget or remain silent about side effects.
For example, recently ephedrine cannot be purchased at a pharmacy at all, since it is recognized as a narcotic drug. Its main effect is stimulation of the sympathetic nervous system. Adrenergic receptors are stimulated. As a result of these processes, cardiac activity is activated: the pulse increases, glucose levels and blood pressure go off scale, and breathing quickens.
Excitement and temperature rise occur, which leads to increased training activity and fat burning. However, in case of an overdose, vomiting, convulsions, and clouding of consciousness are possible. A pronounced withdrawal syndrome occurs when the drug is stopped. You may feel depressed and lethargic. That is, in fact, addiction arises!
Therefore, instead of ephedrine in its pure form, they began to use an analogue - broncholithin, which contains this narcotic component.
Caffeine has approximately the same effect, but its effect is based on stimulation of the sympathetic division of the ANS. But the effect of this substance is not as pronounced as the effect of ephedrine. When used together, it enhances the effect of ephedrine.
And when you add aspirin to this “cocktail,” you can reduce your appetite.
Aspirin has disappeared from pharmacies - Instant coffee for weight loss. Forum, discussions
Aspirin for weight loss can be used by everyone. And scientists from the University of Dundee (in the UK) report in the journal Science that aspirin can also be used as a means of losing weight . ASPIRIN CARDIO - instructions for use and description of the drug, reviews of the drug ASPIRIN CARDIO - minimum price and where to buy ASPIRIN CARDIO, ASPIRIN CARDIO during pregnancy - answer to Health@. aspirin cardio forum .
Super weight loss (ephedrine/caffeine/ aspirin ). All bodybuilders have basically one thing in common - the desire to build more muscle; This is the essence of bodybuilding - building a body that is more voluminous, stronger. Aspirin face mask . aspirin tablets at home, and almost every one of us has them in our makeup bag. On the forum . Winter menu for weight loss . Pomegranate is an ancient apple of beauty and health.
The following question arose: the doctor prescribed cardio- aspirin . I looked at the ingredients: acetylsalicylic acid, just like in regular aspirin . Just aspirin costs 8 rubles, and cardio- aspirin costs more than 100.
How realistic is it to lose weight with aspirin?
As a rule, just taking aspirin has no effect. It must be taken during a diet, as well as as part of a special complex, which also contains other components, such as ephedrine and caffeine. There is even such a concept - “ECA diet”, where ECA is the first letters of three components:
The use of such medications, as those losing weight on this diet believe, leads to the following effects:
- appetite becomes less pronounced,
- the body loses excess fluid,
- fat cells are more actively broken down.
All processes in the body accelerate, which leads to a feeling of vigor and a surge of energy. Taking aspirin makes it easier to force yourself to go to the gym and feel almost no fatigue during exercise.
Contraindications
Aspirin is prohibited for the following diseases:
- gastritis, ulcer;
- heart failure;
- gastrointestinal bleeding;
- hemophilia;
- liver and kidney failure;
- asthma attacks induced by taking NSAIDs;
- spider veins on the skin;
- vitamin K deficiency;
- thrombocytopenia.
Do not take acetylsalicylic acid tablets during pregnancy or while breastfeeding.
Aspirin in sports
/ Home / Auxiliary menu / Library / Nutrition, sports nutrition (dietary supplement) / Nutrition, sports nutrition (dietary supplement) - 2 / Aspirin in sports"Aspirin in sports"
Today we will talk about a drug that can be found in almost every home medicine cabinet. People resort to it at the slightest ailment without any consultation with a doctor - it has a reputation as an almost harmless medicine. In addition to its well-known formula, widely advertised in domestic and foreign media, it is also found in so-called fat burners (where it is represented by extract from white willow bark - White Willow). So what is aspirin? How and for what indications should it be used?
Aspirin or acetylsalicylic acid was invented in 1869. It is a derivative of salicylic acid (see formulas), which has been used as an antipyretic and anti-inflammatory agent. Its sodium salt, called “salicylic soda,” remained in the arsenal of doctors for a long time and is still used in some cases. However, pure salicylic acid is an extremely caustic substance and has a harmful effect on the mucous membranes of the gastrointestinal tract. Acetylsalicylic acid is less caustic mainly due to the “closed” phenolic hydroxy group.
Application in medicine
Aspirin is one of the most popular non-steroidal anti-inflammatory drugs. This is due to the breadth of its therapeutic action, and therefore its suitability for pain of almost any origin. As an anti-inflammatory, it is used for diseases and disorders accompanied by severe inflammation (in particular, dental diseases); as an antipyretic - for colds; as an analgesic - for headaches, muscle pain, joint pain.
Since salicylic acid derivatives prevent platelet aggregation (the colloquial expression: “thin the blood” is not entirely correct, since blood viscosity hardly decreases), they have found use in the treatment of a number of diseases of the cardiovascular system. For example, they are used to prevent blood clots after myocardial infarction, with increased blood clotting.
Other derivatives of salicylic acid are also used in medicine - salicylamide (anti-inflammatory and analgesic), methyl salicylate (also anti-inflammatory, but only for external use).
Possible combinations and compatibility with other medications
A huge number of drugs are produced containing aspirin, both separately and in certain combinations (for the list, see Appendices 1 and 2).
In drugs that are predominantly analgesic (such as Citramon and Askofen), aspirin is combined with other drugs of similar action. In this case, the dose of aspirin is reduced to 50-100 mg per dose. Very often, caffeine is added to the finished forms, which helps relieve spasms of cerebral vessels and thus increases the effectiveness against migraines.
Mixtures of aspirin with large doses of vitamin C (for example, Aspirin UPSA) have found quite widespread use. This combination provides a milder effect on hematopoiesis and relieves some of the side effects.
In addition, soluble forms - effervescent tablets - are absorbed faster and have a gentler effect on the mucous membranes. Alas, the final solution contains little ascorbic acid, and it has to be taken additionally.
Enteric-soluble forms (for example, Thrombo ACC) do not cause damage to the gastric wall, and can be used in the presence of ulcers or gastritis.
It should be borne in mind that aspirin enhances the effect of other anticoagulants and somewhat weakens the effect of diuretics. Taking it together with most medications requires prior consultation with your doctor.
Aspirin in sports
Since all elite sports are in one way or another associated with inevitable microtraumas and pain, aspirin is mainly taken by athletes as an analgesic. However, the dosages in this case are several times higher than those recommended by doctors. Aspirin is most often taken in the presence of joint damage due to its antirheumatic properties.
Where there is a high risk of thrombosis due to dehydration (prolonged competition at elevated temperatures), aspirin can also be used as a means of preventing the formation of blood clots. In this case, soluble forms enriched with vitamin C are preferred.
The combination of aspirin + a large (several grams) dose of vitamin C is very effective as an anti-flu drug; it works well even in cases where the athlete’s immune system is “damaged” by long-term training. However, in this case, additional insurance with B vitamins should be provided.
Quite curious was the property of acetylsalicylic acid to extend and possibly enhance the effect of thermogenic drugs. This is especially true for the very common “package” ephedrine - caffeine. Unfortunately, there is one peculiarity here. Although the required doses in this case do not exceed pharmaceutical ones - 1 tablet weighing 350-500 mg per 20 mg of ephedrine and 200 mg of caffeine - with the recommended three times daily dose you already receive 1050-1500 mg of aspirin, which, of course, is too much. In our opinion, the effect is not worth the risk.
Dosages and methods of administration
In medicine, doses of 0.25 to 1 g per day are used, usually in 3-4 doses. When taken independently, it is recommended to use no more than 1 tablet per day (the weight of the tablet in our country is 250-500 mg and for children it is 100 mg, in the USA it is 350 mg). It is best to take the drug after meals in crushed form.
As an analgesic and antirheumatic drug, aspirin is taken in relatively small dosages, since at doses of more than 1 g per day the antithrombotic effect is much stronger. The duration of the course is no more than a week!
Side effects
The irritating effect of aspirin on the mucous membranes of the stomach has already been mentioned above. Since hydrolysis to salicylic acid is necessary for the effect to occur, such exposure may lead to ulcers with long-term use. There have even been cases of death after taking large doses: perforation of the gastric wall occurred.
In addition, long-term use of salicylates is fraught with anemia due to inhibition of hematopoiesis. In case of low blood clotting (hemophilia), the drug is generally contraindicated. It has been shown that if you are prone to asthma, even a single dose of aspirin can trigger an asthmatic attack.
All these side effects lead to the fact that they try to replace aspirin with more harmless analgesics, and components that provoke the development of disorders are removed from ready-made forms. For example, instead of the old Citramon, Citramon-P is now used, in which phenacetin is replaced by paracetamol. For pain of non-inflammatory origin (headaches), paracetamol is more acceptable, but it is ineffective for inflammation and should be replaced with ibuprofen or indomethacin.
CONCLUSIONS
Despite its more than 100-year history, aspirin is a highly effective analgesic and anti-inflammatory agent. That is why it has not yet been excluded from the range of medicines. However, it should be used with caution, keeping in mind the large number of side effects. In some cases, aspirin should be replaced with drugs such as paracetamol, indomethacin, butadione, and in case of acute pain - with stronger analgesics (Tramal).
Annex 1.
Anopyrin, Apo-Asa, aspivatrin, aspilite, acylpirin, bufferin, Jasprin, Colfarit, laspal, Mikristin, Novandol, Novooan, Plidol, Ronal, Salorin, Thrombo ACC, Elkapin, Acesal, Acetylin, Aspisol, Astrin, Ataspin, Bebaspin, Bispirine , Caprin, Cetasal, Clariprin, Darosal, Durasal, Endosalil, Eutosal, Helicon, Isopirin, Monasalyl, Novandol, Panspiril, Polopyrina, Prodol, Rodopyrin, Ronal, Ruspirin, Salacetin, Saletin, Temperal, Vicapirine, Zorprin
Appendix 2.
Characteristics of some complex preparations containing aspirin
Citramon-P
In 1 tablet: acetylsalicylic acid 0.24 g; paracetamol 0.18 g; caffeine 0.03 g; cocoa 0.0225 g; citric acid 0.005 g. An analgesic used for pain, primarily of a non-inflammatory nature. Relieves lethargy characteristic of headaches caused by overwork.
Sedalgin N
In 1 tablet: acetylsalicylic acid and paracetamol - 0.2 g each; phenobarbital 0.025 g; caffeine 0.05 g; codeine phosphate 0.1 g. Unlike the previous drug, it has a mild sedative and hypnotic effect. Effective for neuralgia and neuritis. Aspirin with vitamin C (UPSA)
The soluble tablet contains: acetylsalicylic acid 0.4 g; ascorbic acid 0.24-0.3 g; sodium bicarbonate and citrate. They are easy to use, although some of the ascorbic acid is destroyed when preparing the solution.
Acelysin
A mixture of lysine and glycine acetylsalicylate (9:1). Crystalline powder. Available in two forms: for injection (in sterile bottles of 1 g) and for drinking (0.2 g of acelysine and 1.4 g of sugar with citric acid and food essence).
The addition of lysine dramatically enhances the effectiveness of the drug and reduces side effects. It is used as a local analgesic for postoperative pain, as an antipyretic and antiplatelet agent.