The drug mildronate is a non-steroidal drug and is widely used in cardiology and ophthalmology. It is used to restore cell metabolism after intracellular oxygen starvation (hypoxia) and poor blood supply (ischemia). Mildronate is often used by athletes during heavy strength loads.
Mechanism of action for weight loss
The active component of the drug is similar in structure to the substance that is found inside the cells of the body. Meldonium dihydrate improves metabolism and energy supply to tissues. With the help of meldonium, the body becomes more resilient, blood circulation improves, symptoms of overexertion disappear, the body's resistance to diseases increases, and the amount of subcutaneous fat decreases. Additionally, the product has a vasodilating effect, supports and protects the heart muscle.
For weight loss, the product can be used in combination with other products. Weight begins to decrease only in the case of joint physical activity.
What properties does the drug Mildronate have?
Mildronate belongs to a group of drugs that activate metabolic processes in the body and provide cells with energy. It is great for strength athletes who train intensely in an aerobic style. You can buy it at the pharmacy only with a prescription.
In sports, this drug is used for the following purposes:
- increase performance and reduce bodybuilder fatigue;
- make training more effective;
- protect the heart muscle from the action of free radicals and lactic acid, which are formed as a result of power loads;
- prevents fatty acids from accumulating in cells;
- activates the breakdown of glucose.
It has been proven that the action of mildronate is similar to the action of insulin, as evidenced by the following effects:
- after its use, the body recovers much better after training or competition;
- increases the body's endurance;
- protects against stress;
- improves the activity of metabolic processes in the cerebral cortex;
- athletes taking this drug show better results compared to others.
It is advisable to prescribe Mildronate to athletes to restore the body after injuries, treat overtraining syndrome, in rehabilitation after surgical interventions and decreased physical performance.
Dosage and use of the drug
To get rid of excess weight, the drug must be taken orally in the form of capsules or given injections. The dosage depends on the dosage form:
- Injection. There is no need to dilute it. The initial dosage is 5 ml per day intravenously. Can be divided into 2 doses. The duration of therapy is from 7 to 14 days. Then you need to switch to taking capsules.
- Gelatin capsules. It is recommended to take 500 mg twice a day. Reception is carried out for 10-20 days.
In case of impaired liver and kidney function, the dose should be reduced. The drug has a stimulating effect, so you need to take the drug before lunch.
Mildronate dosage.
Efficiency for athletes
Over the past few years, the drug has been actively used by bodybuilders and athletes. The universal composition of Mildronate helps athletes recover much faster after the stress they have endured. The desired effect is achieved due to the fact that the body can more efficiently use its resources, which are endowed by nature. The action of the product is aimed at ensuring that muscles and other tissues can quickly adapt to stressful conditions, as well as physical and psychological stress.
Thus, Mildronate helps accumulate unoxidized fatty acids in the body’s cells, helps regulate oxygen supply to cells, activates glycolysis, improves muscle nutrition, thereby increasing the effectiveness of training and reducing fatigue.
But do not forget that since January 1, 2020, the drug is on the current list of prohibited substances in sports of the World Anti-Doping Agency, so it cannot be used during competitions.
Contraindications
The drug is contraindicated in the following conditions and diseases:
- pregnancy;
- lactation period;
- allergy to meldonium;
- increased intracranial pressure;
- severe liver and kidney diseases.
It is not recommended to use the product under 18 years of age.
Indications and contraindications.
Indications for use
Despite the fact that athletes actively use Mildronate for weight loss, medical professionals often prescribe this drug to their patients to combat certain diseases:
- Decreased performance.
- Chronic heart failure.
- Great physical and mental overstrain.
- Cardiomyopathy arising from serious hormonal disorders.
- Diabetes.
- Osteochondrosis of the cervical spine, as well as other conditions in which blood circulation in the brain is impaired.
- Treatment of strokes.
- Myocardial infarction, angina pectoris, coronary heart disease.
- For alcoholism.
Side effects
The drug is well tolerated by the body, but sometimes side effects occur:
- decreased blood pressure;
- dyspepsia;
- increased excitability;
- heart rhythm disturbance;
- redness and itching of the skin;
- runny nose;
- dyspnea;
- insomnia;
- angioedema;
- nausea and vomiting.
In case of an overdose, loss of consciousness, deterioration in the functioning of the entire body, and anaphylaxis occur. Side effects are rare and may indicate individual intolerance to the components of the drug.
Overdose and special instructions for the drug Mildronate.
The effectiveness of Mildronate in weight loss
Mildronate is not intended for weight loss, but according to reviews it is excellent for weight loss. To increase the effectiveness of the drug, you need to eat right and lead an active lifestyle. The product is well tolerated by the body and within 2-3 weeks, subject to physical activity, helps to lose excess weight. Athletes use the product to build muscle mass in a short time. This drug is a dope that has a stimulating effect on the body. During training, fatigue is not felt as much, and the body is able to withstand heavy loads.
The drug helps you get used to physical activity and play sports comfortably. The body's potential is used more rationally, and athletic performance improves. While taking the drug, the body quickly gets rid of excess weight, as the response to various types of stress improves.
Reviews from bodybuilders about Mildronate
The negativity on the part of this category of athletes is quite understandable. Since the drug is designed, first of all, not for the growth of muscle tissue and not for the rate of synthesis of protein supplied with food, its use during weightlifting is almost completely meaningless.
The picture is completely different among those sports in which the athlete requires a pumped heart and excellent breathing. As well as internal organs that are accustomed to withstand the athletics load. Reviews from boxing athletes about Mildronate indicate that athletes have become much more resilient. This is the meaning of the drug’s action - primarily to increase aerobic endurance, and strength indicators will increase relatively slowly, but progress will certainly appear in them too.
Drug interactions
Before using the product, it is necessary to study drug interactions with other drugs:
- the effect of antihypertensive drugs and cardiac glycosides is enhanced;
- nitroglycerin, alpha-blockers and Nifedipine can lead to a decrease in blood pressure and heart rhythm disturbances;
- Taking other meldonium medications is contraindicated.
You can take anticoagulants, long-acting nitrates, diuretics, bronchodilators and antiplatelet agents together.
Analogues of Mildronate
If necessary, you can purchase analogues of the active substance:
- Vazonat;
- Vasopro;
- Metamax;
- Methonate;
- Mildralex-Health;
- Milcardil;
- Olvazol;
- Ripronate;
- Celebis;
- Trimedronate.
Before replacing with an analogue, you must read the instructions. Contraindications, side effects and dosage regimens are indicated there.
Reviews
Anastasia, 25 years old : I lost 8 kg of excess weight and decided to build muscle mass. We recommended this remedy to improve the body’s endurance and achieve results faster. I took 5-6 capsules a day. I was pleased with the effect of the application. The muscles began to appear, the body became more prominent and fatigue during training was not felt as much. After 20 days of therapy, insomnia began and the dose had to be reduced. The condition did not change after finishing treatment. The feeling is good, the body is full of strength, apathy has disappeared.
Julia, 32 years old : I learned from reviews that the product helps to lose weight. I didn’t want to buy it in ampoules because I’m afraid of injections. I took 250 mg capsules 4 times a day. I began to weigh 3-4 kg less. Heart rate normalized and memory improved. About 2 weeks have passed, and I feel a surge of strength and lightness in my body. I don’t recommend taking it on your own for weight loss, because the cause of excess weight may be a hormonal imbalance. Now I feel great and have a healthy heart. There were no side effects, although sometimes I felt severe mental excitability.
Igor, 28 years old : I bought the drug to improve my condition due to physical and mental exhaustion. I heard that the product improves the supply of oxygen to cells. I work a lot, study and go to the gym regularly. After using it, I felt stronger, began to get enough sleep at night, and in the morning I feel alert instead of drowsy. I cope with routine tasks quickly and have energy left to go to the gym. I took it for 3 weeks after training, but during this time I lost 5-6 kg. I stopped taking it because I don’t want to lose any more weight. The product can be taken by girls who train and dream of a slim body.
Oleg, 40 years old : Meldonium is the active ingredient of this medicine, which improves metabolism. Tablets and capsules should be taken for a long time and together with regular physical activity. The product goes well with the diet and it is not so difficult to switch to a low-calorie diet. The product is excellent for diabetes in combination with Metformin. Body weight decreases, the concentration of glucose in the blood decreases. The doctor explained that the risk of developing acidosis is reduced. An effective remedy. Weight decreases and remains stable for a long time.
Marina, 38 years old : Diagnosed with vascular atherosclerosis. The doctor prescribed the drug in the form of injections. I went to the clinic for 10-14 days and lost 2 kg. It was a surprise that the excess weight began to go away. I can’t go to the gym because of heart pain, so I was happy when I saw the number on the scale. After taking the capsules I lost another 3 kg. My heart began to work better, my figure improved and I began to think much faster. For parents, the drug helps reduce the frequency of attacks due to angina pectoris.
Composition and release form
The drug is not a prescription drug. Anyone can purchase it in almost every pharmacy chain. The main active ingredient of the drug is meldonium, the effectiveness of which has been clinically proven to eliminate lack of energy and accelerate metabolism in tissues.
The drug has several forms of release - injection (ampoules), syrup and capsules for oral administration. The most effective is injection, in which the medicine is injected directly into a vein. To achieve an effective concentration of meldonium in the blood, you should take about five to six capsules at a time. Meldonium is not absorbed so quickly through the gastrointestinal tract. When administered intravenously, it is instantly distributed through the bloodstream to every corner of the body.