November 21, 2020 Admin Home page » Pharmacology
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What is turinabol, scope of application, dosage and methods of administration, side effects.
The drug Turinabol (often called “turik”) is in some ways the younger brother of methandienone. Since it is similar to methane in its effect on the body and in its structure. The difference in it is the presence of a chlorine atom in the 4th generation. Turinabol was discovered in the 60s in Germany. Initially, it was used for both men and women in athletics; a full turinabol course helped to increase speed performance, but at the same time an increase in strength was observed, which is why it began to be introduced into strength sports.
Oral-Turinabol[edit | edit code]
Yuzhakov Anton TURINABOL description of the drug, effects, action and dosage
Yuzhakov Anton TURINABOL HOW TO CORRECTLY USE ANALYSIS ON TURINABOL
Turanabol from the Balkans Turinoger from Gerth Pharmaceuticals (100 tablets of 10 mg each)
Turinabol (Oral)
(chemical 4-chlorodehydromethyltestosterone)
is an anabolic steroid that is similar in effects and chemical structure to methandrostenolone. The word “oral” in the name means that this anabolic drug is taken orally (orally). The difference from methandrostenolone is that turinabol contains an additional chlorine atom at the fourth carbon atom. The drug was first developed by the German pharmaceutical company Jenapharm and patented in 1961.
Synonyms:
turinoger, turanabol, turamoth, turanabol, turik, turinabolos, turinover
Steroid profile[edit | edit code]
- Anabolic activity - 180%
- Androgenic activity - 50%
- Aromatization (conversion to estrogens) - absent
- Suppression of the hypothalamic-pituitary-testicular axis - moderate-high
- Liver toxicity - moderate
- Method of administration: orally (in tablets)
- Half-life - 16 hours
- Detection time: up to 250 days (long-lived fat-soluble metabolites)
Maximum plasma concentration 3 hours after administration.[1]
Legal status[edit | edit code]
Dehydrochlormethyltestosterone, its salts, isomers, esters, all dosage forms and trade names are included in the list of potent substances on the basis of Decree of the Government of the Russian Federation of December 29, 2007 No. 964. Criminal liability entails: illegal production, processing, acquisition, storage, transportation or forwarding for the purpose of sales, as well as illegal sale, or equipment for its production or processing.
Large size
dehydrochlormethyltestosterone is 10 g or more.[2]
Historical background[edit | edit code]
To achieve success in the Olympic Games, starting in the 1960s, East Germany developed a number of highly effective anabolic steroids, including the drug oralturinabol. The developers described it as a combined version of Methandrostenolone and Oxandrolone with a moderate anabolic effect (comparable to testosterone) and a low incidence of side effects. The creator is Albert Stachowiak.
Trademarks of Turinabol release
According to consumers, the popular brands under which Turinabol is produced are:
- Turinover (Oral-Turinabol) Vermodje (Moldova);
- Turinabolos British Dragon (Thailand);
- Turinabolos Balkan Pharmaceuticals (Moldova) - the most popular in Russia;
- Turinabolos Pharmacom Labs Inc. (China);
- Turinotabs G-Tech Pharmaceuticals (China);
- Turinadrol-10 Lyka Labs Ltd. (India);
- Oral-Turinabol Jenapharm (Germany).
Description[edit | edit code]
The drug can be characterized as Methandrostenolone without the effect of fluid retention in the body.
This is a delayed acting steroid. During a course of turinabol, weight, strength and definition progress very slowly, but according to athletes, these results are of better quality.[3]
Another distinctive feature of the drug is the absence of estrogenic effects (since it does not undergo aromatization due to the addition of a chlorine atom to the molecule), that is, side effects such as fluid accumulation, gynecomastia, etc. practically never occur. Although there are reviews that report the development of gynecomastia, the mechanism of development of which remains unclear. The most likely reason is the presence of methyltestosterone in the composition, which is due to the peculiarities of synthesis.
It has also been determined that the concentration of SHBG decreases, therefore the level of free testosterone in the blood increases.[4] There is evidence that turinabol reduces the risk of blood clots in the blood vessels and heart.
Indications for use
The drug can be used as an adjuvant in conditions caused by protein starvation and characterized by a negative nitrogen balance. Indications for use are:
- asthenia and cachexia of various origins;
- extensive burns;
- osteoporosis;
- anemia (chronic hemolytic, hypo- and aplastic, associated with tumor processes or chronic renal failure);
- lymphoma and leukemia ;
- muscle atrophy in patients with AIDS ;
- idiopathic thrombocytopenia.
It is considered appropriate to prescribe Turinabol to elderly people with exhaustion or malnutrition, patients who have been receiving GCS for a long time, during the period of convalescence after surgery, injuries and infectious diseases;
In pediatrics, the drug is used for growth retardation, loss of nutrition, and anorexia .
Course[edit | edit code]
Test results at the end of the course of oral-turinabol (the last column shows the norms)
During preparation for the Olympic Games, the optimal dose of the drug was selected, which caused a minimum of side effects - 20-40 mg per day, divided into three doses [5], but bodybuilders these numbers are often neglected, increasing the dosage to 100-150 mg per day [6].
The drug can be used both when gaining muscle mass and when cutting. A course of turinabol does not require the inclusion of gonadotropin (if it does not exceed 6-8 weeks), however, PCT is carried out with estrogen receptor blockers (tamoxifen). Turinabol monocourse is considered one of the simplest and safest in bodybuilding, therefore it is often recommended for beginners. For the first course, the optimal dosage is 40 mg/day for 6 weeks. This allows you to get impressive results, both in terms of an increase in quality muscle mass and in the progress of speed and strength results.
For gaining muscle mass, a combined course of Turinabol (20 mg per day) + testosterone enanthate 250 mg per week (or + sustanon) is better suited. Duration on average 6 weeks. First, enanthate is discontinued, and after a week turinabol is discontinued.
Athletes who are not interested in gaining weight and seek to increase speed and endurance (boxers, wrestlers, runners, etc.) are recommended to use lower doses - 10-20 mg per day.[7]. However, it should be taken into account that recently Oralturinabol has become a problematic steroid in terms of anti-doping control, since recently discovered (2012) long-lived metabolites are detected within six to eight months. Recent developments in chromatography-mass spectrometry have made a major contribution to this incredibly long detection period.
It should also be noted that there are a lot of fakes on the black market (sometimes with a different active ingredient), as a result of which the results obtained do not always live up to expectations.
Turinabol for women
Due to the fact that the product does not cause virilization (the appearance of signs of the male type in women - a rough voice, enlargement of the clitoris, menstrual irregularities), it can be used by girls. Indications for use include preparation for a fitness bikini, “drying” and modernization of muscles, and getting rid of subcutaneous fat. For women, a dosage of 15-20 mg/day is recommended for a course of 4-6 weeks and post-cycle therapy with Tamoxifen or Clomid.
Side effects[edit | edit code]
Turinabol is a 17-alkylated anabolic steroid, which makes oral administration possible, but creates a toxic effect on the liver comparable to methandrostenolone. In general, side effects are quite rare and are most often associated with exceeding the duration of the course and high doses. This drug strongly suppresses the secretion of your own testosterone. Erectile dysfunction is possible after withdrawal; there have been cases of premature ejaculation.
Liver disorders
: cholestatic jaundice, necrosis of hepatocytes with liver failure, liver cancer. From the biochemical parameters, an increase in the level of bilirubin, alkaline phosphatase and transaminases is determined. Cholestatic jaundice can develop after 6 months or more (it is of toxic origin) and is manifested by stasis in the bile capillaries with hyperbilirubinemia and increased alkaline phosphatase activity. When used for several years, the incidence of liver cancer may increase.
There was an official report of carcinogenic effects over 5 years of use of turinabol in relatively high doses.[8][9]
Endocrine disorders
: Turanabol, less often than other drugs in men, can cause: inhibition of spermatogenesis and impotence (secondary to a decrease in the secretion of gonadotropins and testosterone levels with testicular atrophy and oligospermia); prostatic hypertrophy (mainly in older people); epididymitis; priapism. Boys may experience premature puberty, frequent erections, and the risk of stunted growth.
Neurological disorders
: agitation, confusion, insomnia, depression.
Metabolic disorders
: decreased glucose tolerance; increased levels of low-density lipoproteins (LDL); acceleration of creatinine excretion; increased levels of creatine phosphokinase; edema is relatively rarely observed due to minor sodium and water retention; retention of potassium, calcium and phosphorus. Hypercalcemia may develop in patients with prolonged bed rest.
Others
: During puberty, the epiphyseal zones of bones may close prematurely with growth retardation.
In women, the drug can rarely cause
: decreased secretion of gonadotropins; virilization phenomena (acne, hirsutism, deepening of the voice, increased libido, menstrual irregularities, clitoral hypertrophy, muscle development). Pregnant women may develop virilization of the female fetus. The frequency of these side effects with Turanabol is low.
special instructions
The drug is highly effective, so it is useful to study the rules for its use. This is indicated in the special instructions section of the instructions:
- does not cause virilization, but if signs appear (deepening of the voice, clitoromegaly in women, acne, hirsutism), you should stop taking it;
- taking large doses of tablets requires periodic monitoring of hemoglobin and hematocrit due to the risk of developing polycythemia;
- the drug is used with caution in pediatrics in children;
- During use, it is better to follow a protein diet, avoid fats, fasting and glucose, drink plenty of fluids and take vitamins.
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Qualitative sample[edit | edit code]
The presence of halogen (chlorine) in the turinabol molecule makes it possible to detect a fake even at home. There is a qualitative method for determining halogens in a sample - the Beilstein test.[10]
To perform the experiment, you will need a gas burner (or alcohol lamp), copper wire and a sample that we will analyze. The sample is ground to a homogeneous powder. We bend the end of the copper wire, making a loop, and hold it in the flame of the burner until the greenish tint of the flame disappears. Next, remove the wire from the flame, place a dry sample (a grain of sand) on the loop and bring it back into the burner flame. If it turns green, the test is positive.[11]
You can also pre-dissolve the sample, for example in ethyl alcohol. To do this, you need to take a small glass, pour literally a few drops onto the bottom (there should not be a lot of alcohol), and dissolve a small amount of the sample in it (at the tip of a knife). The wire is lowered into the resulting solution, everything else is as described above.
Turinabol price
The cost of the drug depends on who the manufacturer is and how many tablets are contained in the pack. You can purchase Turinabol through pharmacies or online stores, special departments for bodybuilders. Approximate metropolitan prices for the drug and analogues are shown in the table:
Name of the product | Internet price, in rubles | Pharmacy cost, in rubles |
Turinabol 100 tablets | 1600 | 1800 |
Stanozolol 100 pcs., 10 mg | 2000 | 2100 |
Oxandrolone 20 pcs., 10 mg | 1500 | 1600 |
Notes[edit | edit code]
- https://www.ncbi.nlm.nih.gov/pubmed/1798729
- https://base.garant.ru/12158202/#block_3000
- Daniels, R. C. (February 1, 2003). The Anabolic Steroid Handbook. Richard C Daniels. p. 80. ISBN 0-9548227-0-6.
- The pharmacokinetics of Oral-Turinabol in humans] Pharmazie. 1991 Sep;46(9):650-4. German.
- https://forums.steroid.com/showthread.php?199812-Anabolic-Review-Steroid-Profile-Oral-Turinabol-%28Chlordehydromethyltestosterone%29#.Tm0g6ewmRBk
- https://do4a.com/threads/%D0%A2%D1%83%D1%80%D0%B8%D0%BD%D0%B0%D0%B1%D0%BE%D0%BB.4347/
- Berendonk B. Doping. Von der Forschung zum Betrug. Reinbek bei Hamburg: Rowohlt Taschenbuchverlag. 1992:448pp Clinical Chemistry 43:7. 1262-1279 (1997)
- Department of Urology, Universitaetsklinikum "Carl Gustav Carus," Technical University of Dresden, Dresden, Germany
- Intratesticular leiomyosarcoma in a young man after high dose doping with Oral-Turinabol: a case report. Cancer. 1999 Oct 15;86(8):1571-5.
- https://www.xumuk.ru/encyklopedia/483.html
- The experiment was described and performed by Nikolai Krek, “Chemical Blog”
Contraindications
Contraindications to the use of Turinabol are:
- breast cancer in men;
- prostate adenoma and ;
- malignant tumors of the mammary glands in women accompanied by hypercalcemia
- ovarian cancer;
- severe atherosclerosis ;
- IHD;
- nephrotic syndrome and nephritis ;
- functional kidney/liver failure;
- prostatitis (both acute and chronic);
- pregnancy;
- lactation;
- period before puberty;
- hypersensitivity to the components of the tablets.