Arginine + Ornithine, L-Arginine 500 mg + L-Ornithine 250 mg – 250 capsules

Ornithine (eng. L-ornithine) is diaminovaleric acid, which is involved in the biosynthesis of urea, is a non-essential amino acid that is synthesized in the body. L-ornithine is not part of proteins, but is found naturally in the body in small quantities. It has the ability to convert into arginine. Indispensable in the process of urine formation and excretion. This helps remove toxins from the body. With an active lifestyle, the need for amino acid increases, so it is necessary to use it additionally.

Ornithine: formula

The amino acid L-ornithine was first described by D. Ackerman in 1937. He synthesized a substance from shark liver. Subsequently, as a result of scientific research, scientists established the effect of the drug on the human body.

The formula of ornithine is C5H12N2O2. Externally, it is a colorless substance in the form of crystals that can dissolve in water. In the body , ornithine closely interacts with the amino acid arginine, they are converted into each other. But unlike arginine, it is not part of the protein. Refers to hepatoprotectors and detoxifying agents.

What are the benefits of taking arginine?

1. Nitric oxide.

Recently, scientists discovered that nitric oxide helps build protein in the body, including the growth of bones and ligaments. Some people take arginine supplements for broken limbs, to speed up wound healing, burn recovery, and so on.

Rose's essential amino acid requirement was determined under isocaloric conditions, with the total amount of all amino acids being sufficient. Therefore, the data is often misinterpreted. The average basal intake is about 1 g per branched chain amino acid for a 70 kg adult, therefore too low in hypocaloric conditions. Branched-chain amino acids are essential for the construction of almost all proteins. In case of physical stress, however, energy consumption consumes the main amount.

Excessive amounts of nitric oxide, as well as its deficiency, can be harmful to health. Its level should be normal. Nitric oxide is a free radical and destroys cells. When there is too much of it, it can lead to a weakening of the body’s defenses; when too little, it can lead to the inability to build its own proteins.

2. Increase growth hormone.

Arginine suppresses the action of somatostatin, a hormone that blocks the secretion of growth hormone. At the same time, it promotes the functioning of hormones that stimulate the secretion of growth hormone.

Amino acids are mainly involved in the transfer of nitrogen and energy between muscles and the liver. Unlike other amino acids, they are preferentially degraded in the peripheral organs of skeletal muscle, in the heart muscle and in the kidneys, forming an alternative source of energy for muscles.

When these three amino acid breakdown reactions occur, various intermediates are formed that determine whether the amino acid is ketogenic, glucogenic, or both. Transamination results in the formation of keto acids from branched chain amino acids, which can be separated into activated fatty acids and introduced into metabolism or converted back to an amino acid. An additional pathway under ketoacidotic conditions has been demonstrated in cell cultures and in rodents and mammals.

3. Improve blood circulation.

This increases muscle tone, libido, and brain function. For example, if you take an arginine supplement at night, you will have very vivid and vivid dreams at night. This is precisely due to the activation of the brain. Arginine helps increase endurance during training, reducing stress on the heart.

Ornithine: properties

Ornithine is found in the body in small quantities, but its effect on human health should not be underestimated. It has unique properties due to its versatility and ability to be converted into other amino acids.

• Ornithine is a precursor to glutamine, proline and citrulline. From it you can get creatine, which is the main source of muscle energy.
• Activates fat burning in the body. To enhance the effect, it is recommended to take it with L-carnitine and arginine.
• Stimulates the formation of proteins, in particular muscle tissue.
• Regenerates liver cells. It is a kind of its protector: it participates in the process of cleansing the liver of toxins and activates the restoration of damaged tissues.
• Without it, the process of removing ammonia from the body, which is formed during the breakdown of proteins and is poisonous to the body, is difficult. Increased nervous excitability was revealed due to the toxic effects of urea on the body.
• L-ornithine strengthens tendons and ligaments and helps them recover from injuries. Scientists have established a high content of the substance in connective tissues and skin, so it is so necessary to maintain a sufficient balance of the substance.
• Stimulates hematopoiesis, oxygen saturation of tissues and removal of harmful substances from the body.
• Normalizes the amount of glucose in the blood.
• Relieves excessive nervous excitability, normalizes falling asleep and promotes healthy sleep and melatonin production.
• Accelerates protein metabolism in diseases requiring parenteral nutrition.

Ornithine and arginine: doctor's opinion

Very often, those trying to lose weight try to find the easiest and most harmless way to do it. Many of them rely on the advice of doctors, who say that this requires using the resources of the human body itself. That is, you should make maximum use of the available amino acids that promote weight loss. The two most famous are ornithine and arginine.

The first allows you to activate weight loss processes during sleep, and the second - during wakefulness. But how do they work? And is consuming additional doses of amino acids harmful to the body? According to doctors, it is ornithine and arginine that are catalysts for weight loss. In order to make such a clear conclusion, a lot of research and experiments were carried out.

It turned out that arginine stimulates the production of nitric oxide, which leads to the restoration of muscle fibers and fat burning. And although it is contained in sufficient quantities in ordinary food products, athletes and those wishing to quickly lose weight are recommended to use it as a food supplement. This amino acid has been known for a long time. But only in 1998, after the Nobel Prize was awarded to three American scientists F. Furchgott, F. Murad and L. Ignarro, they started talking about the miraculous properties of arginine.

The fact is that it is he who is capable of becoming nitric oxide, the benefits of which became known due to a doctor’s mistake. Having mixed up drugs in a study of cardiovascular activity, they found that the named compound not only regulates the functioning of the heart, but is also involved in metabolic processes. Arginine promotes the proper functioning of the nervous system, helps produce enzymes and some hormones.

And thanks to the increase in creatine levels in muscle tissue, it has become a favorite drug of bodybuilders. With a deficiency of arginine, hypertension, diabetes mellitus, pathologies of the reproductive system, obesity develop and growth slows down. To replenish the reserves of this amino acid in the body, it is recommended to eat pumpkin seeds and nuts (pine and walnuts), peas and corn, chicken and pork, eggs and rice. If a person’s daily need for arginine is not met, then it should be taken in capsules with food. Within half an hour, the pill you take will begin to act.

Once in the liver, the amino acid will be broken down into nitric oxide and ornithine. The first component, together with the blood, will carry not only oxygen, but also iron elements throughout the body. Especially a lot of nitric oxide will enter the nerve endings that are responsible for transmitting impulses. Some of it will get into the muscles, which will relax them. But that's not all.

Uncleaved arginine residues will participate in the construction of proteins and muscle formation. In addition, the body will increase the production of testosterone and glucose, and the liver will be cleansed faster and freed from toxins. All the activities of arginine will help improve immunity, harmonious functioning of the endocrine system, improve mood, stabilize blood pressure, prevent atherosclerosis and stroke, and increase the rate of wound healing.

For women, it will be useful for its ability to “remove” fibroids, mastopathy, endometriosis, and cervical erosion. It is also effective in the fight against infertility. But most importantly, arginine will reduce body fat and normalize the activity of the pancreas, eliminating the root cause of diabetes. It seems that this amino acid is a salvation from all troubles.

At the molecular level it looks like this. If there is enough arginine in the body, then it is found in every 23 cells of the body. As soon as any disturbance occurs (a microbe gets in, a cyst grows, etc.), it immediately sends a signal to the brain. Thus, the body can cope with the disease itself at the initial stage. It is arginine, called alpha-amino-beta-glaunatin-valeric acid in scientific circles, that is entrusted with the role of a natural informant.

According to Dr. Valentin Fuster, President of the American Heart Association, the discovery of the functions of nitric oxide was the most important in the history of cardiovascular medicine. Ornithine is rightly called a relative of arginine. It is also an amino acid that stimulates the release of insulin and growth hormones. It is classified as non-essential and is not found in proteins. But it is still popular among athletes, as it stimulates muscle growth.

In terms of weight loss, both ornithine and arginine are good fat burners. It is the first component that will help maintain good athletic shape for a long time in response to training, sleep and food intake. Its popularity is explained by its ability to stimulate the secretion of growth hormone accumulated in the pituitary gland. As a result, proteins are synthesized that burn fat and grow muscles.

In addition, ornithine is considered a good hepatoprotector, because it protects the liver from the effects of toxins. It is involved in both urine formation and ammonia excretion. Its other functions include strengthening the immune system, increasing the rate of wound healing, reducing the amount of urea, calming the nervous system and maintaining acid-base balance.

These results can be achieved by taking 10 grams of ornithine daily. Although the exact dosage does not yet exist. But it is better to use ornithine and arginine together. It is advisable to find out the doctor’s opinion on this matter, since in some diseases one should be wary of artificially replenishing the body with amino acids. These two building blocks of proteins are in constant interaction. Ornithine is released from arginine, and the latter is formed from the former.

These cyclical transformations occur constantly, so precautions for one also apply to the other. It is better to choose ornithine as a food supplement. It is taken on an empty stomach with water or juice. Dietary supplements with ornithine are contraindicated for children, women during pregnancy and lactation, as well as those suffering from schizophrenia. Today there are many types of drugs containing the described amino acids.

The best effect can be achieved if you take both ornithine and arginine at the same time. According to recent studies, consuming 1 gram of these acids every day for a month significantly reduces the percentage of body fat. There is other information that indicates the effectiveness of ornithine dosages in the range of 10-15 grams per day. Thus, along with the desire to lose weight, taking the drugs described will help get rid of some diseases and improve the general condition of the body.

Ornithine: in products

Contained only in plant foods, just like beta-carotene. It is not found in animal products. In the natural environment, ornithine can be found in products such as royal jelly of bees and bee drone brood, nuts and pumpkin seeds. The amino acid content in the products is insignificant and cannot satisfy the daily needs of athletes. Therefore, there is a need to take amino acid in the form of dietary supplements.

Ornithine: application

Among people who have recently started playing sports, ornithine is still gaining popularity. Whereas for professional athletes it is included in the list of mandatory nutritional supplements.

Application in sports

• Breakdown of fat deposits during drying.
• Increased muscle mass in bodybuilders.
• Maintaining immunity.
• Activation of oxidative processes.
• In the process of fat breakdown, additional energy is released, giving a new boost of strength to continue training.
• ornithine will provide strength for it .

Application in medicine

Doctors prescribe the amino acid ornithine as part of the treatment of diseases such as:

• Increased level of urea in the blood.
• Kidney failure.
• Liver diseases. Normalizes liver function and cleanses it of toxins.
• Hepatitis.
• The active additive helps restore tissue after burns and has a regenerating effect. Visibly increases skin elasticity.
• Helps in the fight against excess weight, breaking down fat and giving muscles additional energy for training. Losing weight with ornithine becomes comfortable.
• Successfully copes with the manifestations of depression, having a calming effect.
• The detoxification capabilities of amino acids are used in the complex treatment of cancer.

What is the amino acid ornithine and its role in the body?

The organic amino acid ornithine plays an important role in human life. Due to the fact that the amino acid performs the main functions of our body, it has found extensive use in medicine and sports. The substance was obtained from shark liver tissue in the thirties of the twentieth century. Like many other amino acids, ornithine comes in two forms: L and D types. The form with index L is a substance with high biological activity. It actively participates in metabolic processes, and its action is aimed at accelerating metabolism. By the way, this form immediately enters the bloodstream and does not undergo breakdown processes in the gastrointestinal tract. Ornithine is closely related to arginine, from which it is synthesized. In fact, ornithine is not an essential amino acid, but a conditionally essential amino acid.

Ornithine: analogues

If there are contraindications for use or the consumer is not satisfied with the price, then analogues of the amino acid ornithine . Here are a few of them that are used in the treatment of liver diseases.

1. Artichoke - has choleretic, antioxidant and diuretic effects. Supports and stimulates the cleansing work of the liver. Promotes regular formation of bile, stimulates the digestive function of the body.
2. Silymarin is an extract of milk thistle that supports healthy liver function and improves brain activity.
3. Indole-3-Carbinol is a plant substance obtained from cruciferous vegetables (broccoli) with a high sulfur content. Neutralizes free radicals, promotes detoxification of the body.

You can find cheaper alternatives to ornithine , but there is no guarantee that they will have the same beneficial effects on the body as a natural supplement. Similar medications also include lecithin, dandelion root, and glutathione. 5-HTP improves mood like ornithine , which is important when losing weight.

Ornithine: lysine

Ornithine enhances its effect in combination with other amino acids. They replace and complement each other. An example of this is the combination of ornithine and lysine.

L-ornithine improves body shape, accelerates metabolic processes, and protects the liver. Additional consumption of ornithine will allow the body to get rid of extra pounds, restore the liver and resist depression.

L-lysine helps fight fatigue and restores bone and connective tissue. Necessary for tissue growth and restoration, helps calcium absorption, activates the production of growth hormone.

Ornithine , lysine in combination with arginine enhance the effectiveness of sports not only among athletes, but also among people who care about their health.

Arginine

L-arginine is an aliphatic amino acid that eliminates the aromatic aftereffect during strength training and its additional use as nutritional supplements. Arginine functions as a metabolite in NO synthesis and nitrogen cellular metabolism.

In bodybuilding, the use of this amino acid is due to its pronounced anti-inflammatory effect and stimulating effect aimed at stabilizing angiogenesis.

Arginine is a nitric oxide donor that helps increase the process of anabolism, fat burning and the intensity of growth hormone release into the body.

Ornithine: arginine

1). Active food supplement "Arginine + Ornithine" (750 mg, 100 tablets) from Jarrow Formulas , which contains two important amino acids: arginine and ornithine . Promotes protein synthesis, ensures rapid muscle mass gain. Contains pure amino acids in free form. Arginine, as a component of the drug, is used by muscles to produce creatine, an energy source.

Recommendation for use: from 1 ornithine to 6 per day before training or competitions.

Additional Ingredients: Vegetable sources of stearic acid and magnesium, silica and water, calcium phosphate and cellulose.

Contraindications:

• Not recommended for pregnant women and nursing mothers, as well as children under 18 years of age.
• Do not take if you have low blood pressure or worsening herpes.
• When using medications to normalize blood pressure, you should consult your doctor.

Effect of arginine on growth hormone.

A lot of research has been done on this. I will now give you some of them. The effect of arginine in combination with other amino acids was also studied.

The first study looks at what dose is optimal for increasing growth hormone. We took 3 groups of people. They were given an oral arginine supplement. The first group received 0.04 g of arginine per kg of body weight per day, the second – 0.16 g, the third – 0.28 g.

During the experiment, it turned out that growth hormone increased best in people from the second group. In the first group, growth hormone did not increase enough. In the third group, people often experienced diarrhea and gastrointestinal upset. If a person weighs 75 kg, then 12 grams of arginine per day will give the best effect on his growth hormone, the researchers concluded.

The best results were for those people who were not overweight, but had good physical shape and endurance.

Another experiment, in addition to taking arginine, also included lysine - 1.2 g of each substance. This combination increased growth hormone several times. Read more here.

A combination of arginine and ornithine taken before bed shows good results. Ornithine itself can increase growth hormone. According to some reports, it does this even more powerfully than arginine. If they are taken together, a synergistic effect is obtained.

Ornithine: capsules

Ornithine capsules are the most convenient and safe packaging of a dietary supplement. Each capsule contains a strictly defined dose of amino acid, eliminating overdose. The drug is delivered as intended. After passing through the esophagus, the capsule dissolves in gastric juice and releases the amino acid.

2). L-Ornithine from Now Foods (500 mg, 120 capsules) contains a good dosage of ornithine and is in great demand among customers.

Ornithine plays a major role in the formation of urea. Together with arginine and citrulline, it removes protein breakdown products in the form of ammonia from the body. Restores metabolism. By ornithine into arginine, a healthy balance of arginine is maintained in the body. Possessing unique properties, ornithine can be converted in the body into such necessary amino acids as: glutamate, proline, citrulline and a source of muscle energy - creatine. Contains plant ingredients, suitable for vegetarians.

Recommendation for use: take 3 capsules per day, in the morning, on an empty stomach. Take the drug with water or juice.

How can you increase arginine and all its metabolites in the body?

The first option - the safest and healthiest - is obtained from natural foods. The leaders here are pumpkin seeds (4 grams of arginine per 100 grams of product), sesame seeds (3.5 per 100), pine nuts (3 per 100).

If you choose for children, then pumpkin seeds, in my opinion, are the best option. In addition to arginine, they contain a lot of zinc, iron and antioxidants, which will be useful during the period of active growth.

The second option is to receive it by injection. Arginine injections increase growth hormone tenfold. For this reason, by the way, doctors use injections to determine the state of growth hormone and the functioning of the pituitary gland in humans. But doing this without a doctor, especially for a long time, there is a high probability of harming yourself.

The third option is tablets and powders. The option is good, but it has its drawbacks. Firstly, digestibility is only 20–30%. Secondly, not everyone likes the smell and taste of arginine in its pure form.

There are different forms of arginine. I prefer the AAKG form - arginine or extended-release arginine attached to an alpha-ketoglutarate molecule. AAKG maintains elevated nitric oxide levels longer than pure arginine and is better absorbed. Pure arginine and arginine + ornithine are also normal.

Ornithine: in the pharmacy

The drug is in great demand. Its production worldwide has reached 50 tons per year. Most of the pharmacies on the shelves are products of dubious origin, but you want to buy real ornithine , which is beneficial. There are domestic supplements, but they contain a low concentration of ornithine and there is a high risk of buying a fake.

Well-known companies prefer to sell their products through reliable online stores that have a good reputation among consumers. A link to one of the popular stores is given below. They don’t jack up prices here, and they only sell proven products. The optimal combination of price and quality.

Ornithine: instructions

Before you start taking L-ornithine , you need to read the instructions and consult with a specialist on the rules for using the supplement.

Ornithine: how to take (for adults and children)

When taken orally in the form of tablets and capsules, ornithine is from 3 to 6 g per day after meals with water or juice. Course 10-20 days.

In injection form - 2-6 g per day mixed with a solvent. Course 3 weeks.

The duration of the course of ornithine is determined by a specialist.

The effect of the drug on the children's body has not yet been sufficiently studied, so taking the amino acid is not recommended for children under 16 years of age.

How to minimize side effects?

Arginine from natural foods is the least harmful. Of course, if you don’t eat half a kilo of seeds and nuts. This will make your liver howl quickly. When there is no fanaticism, everything is fine. Plus, amino acids are absorbed perfectly in this form.

The main side effect of injections is that if you receive them for a long time and often, the pituitary gland will exhaust its resource and stop secreting hormones normally. I repeat, it is better not to approach injections without a doctor.

What are the side effects of taking oral medications?

Norm of arginine, ornithine and citrulline per day

equal to approximately 4 g for a child and 6 g for adults. It doesn't matter where you get this quantity from. Side effects begin when the dose of any amino acid exceeds 10 grams per day.

Children and adolescents under 18 years of age are not recommended to use these amino acids in supplements of more than 2 grams per day. Doctors explain this by saying that they may stimulate growth hormone too much. How dangerous this is, I don't know. Probably, in some cases, yes.

In general, side effects include diarrhea, nausea, and headache. These drugs can activate the herpes virus. Mostly arginine. If you have active herpes, then arginine, ornithine, citrulline should be combined with lysine or not taken at all. Lysine suppresses the development of herpes.

If you have low blood pressure, you do not need to take arginine. It dilates blood vessels and lowers blood pressure even more.

Arginine can provoke pancreatic diseases. Exceeding 10 grams per day increases this likelihood. If your stomach hurts after taking the supplement, it would be better to stop taking it. When I took arginine for the first time, I encountered pain in my stomach and left side. It immediately became clear what was going on and I stopped taking the supplement for a while. After 2 weeks I started taking it again, then there was no more pain.

It is highly advisable to have enough antioxidants in your diet along with arginine. These may include antioxidants from foods such as fresh fruits and greens. Can be in the form of supplements: coenzyme q10, lipolic acid, vitamin C. This way you will be able to reduce the harmful effects of free radicals that will inevitably appear if you receive a lot of arginine, especially in the form of pharmacology.

Ornithine: contraindications

Despite the fact that ornithine is found only in plant products, there are several contraindications for use.

• The main ones are acute renal failure and hypersensitivity to the components.
• Ornithine should not be used by pregnant women or nursing mothers. The fact is that the substance is transmitted through breast milk.

Side effects

• In rare cases, nausea or vomiting may occur, in which case the supplement should be discontinued.
• It is not recommended to take the supplement while driving a car, as concentration is reduced.

Cautions

• Not for use by children under 18 years of age. Before use, consult a doctor.
• Store in a cool place out of reach of children.
• Use strictly before the expiration date indicated on the packaging.
• It is recommended to store in a bottle.

How to take arginine preparations?

• It is recommended to take on an empty stomach or 2 hours after meals. It is not recommended to take after too fatty and protein foods. After taking it, do not eat for another 2 hours.
• Try buying arginine tablets (some kind) first to understand how it works for you. If you notice the actions that I listed at the beginning, you can try ordering it in powder. Powder usually costs less per quantity and begins to work faster than tablets. But the taste, as I already said, is specific. If you order it straight away in powder and don’t like the taste, then you won’t be able to drink it for at least a couple of weeks, which means you won’t have time to wait for the results.
• On training days, take arginine before physical activity and before bed, 3–5 g; on rest days, take 3–5 g only before bed. I once tried combining arginine with creatine on training days to increase endurance and strength, and on rest days arginine with ornithine for better recovery. I like it. These combinations work great, you can use them.
• Drink plenty of water (300–500 ml)
• The effect of the tablets occurs in about an hour, from the powder - in half an hour. Take this into account to choose the best appointment time.
• It is not advisable to take it constantly. The body quickly gets used to amino acids and therefore there is no point in taking them in long courses.

Let me explain the last point. When I took arginine with citrulline, the effect was noticeable only in the first week of taking it, pure arginine is the same. Starting from the second week, there were almost no results. As a result, I started taking it only on training days, that is, 3 times a week, 3 grams before bed. After a week of “unloading” use, I started taking it every day again and the sensitivity increased. In my opinion, alternating “unloading/loading” for 1 week is a good way to constantly get results from taking arginine.

Ornithine: price

buy a quality-guaranteed drug with a high concentration of ornithine in an online pharmacy using the link below. Prices here are 2-5 times lower than in Russian online stores. Considering that drugs with low dosages are produced in Russia. Additionally, at affordable prices, you can purchase drugs such as hyaluronic acid, fish oil, coenzyme Q10, pycnogenol and others. All this is guaranteed to be of high quality.